Osmotic demyelination syndrom: case report

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Osmotic demyelination syndrome: case report.

We present a 40 year old man who was admitted to the hospital with convulsions. His final diagnosis was osmotic demyelination syndrome (ODS). We discuss the diagnostic and management challenges and the possible complications of this rare diagnosis.

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The osmotic demyelination syndrome (ODS) has been a recognized complication of the rapid correction of hyponatremia for decades. However, in recent years, a variety of other medical conditions have been associated with the development of ODS, independent of changes in serum sodium. This finding suggests that the pathogenesis of ODS may be more complex and involve the inability of brain cells to...

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A Case of Osmotic Demyelination Presenting with Severe Hypernatremia

Osmotic demyelination syndrome is a demyelinating disorder associated with rapid correction of hyponatremia. But, it rarely occurs in acute hypernatremia, and it leads to permanent neurologic symptoms and is associated with high mortality. A 44-year-old woman treated with alternative medicine was admitted with a history of drowsy mental status. Severe hypernatremia (197mEq/L) with hyperosmolali...

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ژورنال

عنوان ژورنال: East African Medical Journal

سال: 2008

ISSN: 0012-835X

DOI: 10.4314/eamj.v84i10.9568